ReportsCancer
Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells
- Waseem Qasim1,2,*,
- Hong Zhan1,
- Sujith Samarasinghe2,
- Stuart Adams2,
- Persis Amrolia1,2,
- Sian Stafford1,
- Katie Butler1,
- Christine Rivat1,
- Gary Wright2,
- Kathy Somana2,
- Sara Ghorashian1,
- Danielle Pinner2,
- Gul Ahsan2,
- Kimberly Gilmour2,
- Giovanna Lucchini2,
- Sarah Inglott2,
- William Mifsud2,
- Robert Chiesa2,
- Karl S. Peggs3,
- Lucas Chan4,
- Farzin Farzaneh4,
- Adrian J. Thrasher1,
- Ajay Vora5,
- Martin Pule3 and
- Paul Veys1
- 1Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
- 2Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
- 3Cancer Institute, University College London, London WC1E 6DD, UK.
- 4Division of Cancer Studies, Department of Haematological Medicine, King’s College London, London SE5 9NU, UK.
- 5Sheffield Children’s Hospital, Sheffield S10 2TH, UK.
- ↵*Corresponding author. Email: w.qasim{at}ucl.ac.uk
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Science Translational Medicine 25 Jan 2017:
Vol. 9, Issue 374, eaaj2013
DOI: 10.1126/scitranslmed.aaj2013
