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ReportsCancer
Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells
- Waseem Qasim1,2,*,
- Hong Zhan1,
- Sujith Samarasinghe2,
- Stuart Adams2,
- Persis Amrolia1,2,
- Sian Stafford1,
- Katie Butler1,
- Christine Rivat1,
- Gary Wright2,
- Kathy Somana2,
- Sara Ghorashian1,
- Danielle Pinner2,
- Gul Ahsan2,
- Kimberly Gilmour2,
- Giovanna Lucchini2,
- Sarah Inglott2,
- William Mifsud2,
- Robert Chiesa2,
- Karl S. Peggs3,
- Lucas Chan4,
- Farzin Farzaneh4,
- Adrian J. Thrasher1,
- Ajay Vora5,
- Martin Pule3 and
- Paul Veys1
- 1Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
- 2Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
- 3Cancer Institute, University College London, London WC1E 6DD, UK.
- 4Division of Cancer Studies, Department of Haematological Medicine, King’s College London, London SE5 9NU, UK.
- 5Sheffield Children’s Hospital, Sheffield S10 2TH, UK.
- ↵*Corresponding author. Email: w.qasim{at}ucl.ac.uk
See allHide authors and affiliations
Science Translational Medicine 25 Jan 2017:
Vol. 9, Issue 374, eaaj2013
DOI: 10.1126/scitranslmed.aaj2013
Vol. 9, Issue 374, eaaj2013
DOI: 10.1126/scitranslmed.aaj2013
Waseem Qasim
Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Hong Zhan
Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
Sujith Samarasinghe
Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Stuart Adams
Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Persis Amrolia
Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Sian Stafford
Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
Katie Butler
Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
Christine Rivat
Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
Gary Wright
Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Kathy Somana
Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Sara Ghorashian
Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
Danielle Pinner
Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Gul Ahsan
Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Kimberly Gilmour
Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Giovanna Lucchini
Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Sarah Inglott
Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
William Mifsud
Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Robert Chiesa
Great Ormond Street Hospital National Health Service Trust, London WC1N 1LE, UK.
Karl S. Peggs
Cancer Institute, University College London, London WC1E 6DD, UK.
Lucas Chan
Division of Cancer Studies, Department of Haematological Medicine, King’s College London, London SE5 9NU, UK.
Farzin Farzaneh
Division of Cancer Studies, Department of Haematological Medicine, King’s College London, London SE5 9NU, UK.
Adrian J. Thrasher
Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
Ajay Vora
Sheffield Children’s Hospital, Sheffield S10 2TH, UK.
Martin Pule
Cancer Institute, University College London, London WC1E 6DD, UK.
Paul Veys
Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
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