Research ArticleBONE DEGENERATION
RON kinase: A target for treatment of cancer-induced bone destruction and osteoporosis
- Kelsi Andrade1,*,†,
- Jaime Fornetti1,*,
- Ling Zhao1,
- Scott C. Miller2,
- R. Lor Randall3,
- Neysi Anderson1,
- Susan E. Waltz4,
- Mark McHale5 and
- Alana L. Welm1,‡
- 1Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA.
- 2Department of Radiology and Imaging Sciences, Division of Radiobiology, University of Utah, Salt Lake City, UT 84112, USA.
- 3Department of Orthopaedics, University of Utah, Salt Lake City, UT 84112, USA.
- 4Department of Cancer and Cell Biology, University of Cincinnati and Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45267, USA.
- 5Aslan Pharmaceuticals, Singapore 089824, Singapore.
- ↵‡Corresponding author. Email: alana.welm{at}hci.utah.edu
↵* These authors contributed equally to this work.
↵† Present address: Stephenson Cancer Center, University of Oklahoma Health Science Center, Oklahoma City, OK 73014, USA.
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Science Translational Medicine 25 Jan 2017:
Vol. 9, Issue 374, eaai9338
DOI: 10.1126/scitranslmed.aai9338