Research ArticleTransplantation

Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Treg and antitumor CTL function

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Science Translational Medicine  11 Jan 2017:
Vol. 9, Issue 372, eaai8269
DOI: 10.1126/scitranslmed.aai8269

Article Information

vol. 9 no. 372

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication December 18, 2015
  • Resubmitted August 17, 2016
  • Accepted for publication October 10, 2016
  • .

Author Information

  1. Brian C. Betts1,2,3,*,
  2. Anandharaman Veerapathran1,2,
  3. Joseph Pidala1,2,3,
  4. Hua Yang3,
  5. Pedro Horna3,4,
  6. Kelly Walton2,
  7. Christopher L. Cubitt5,
  8. Steven Gunawan3,
  9. Harshani R. Lawrence3,6,
  10. Nicholas J. Lawrence3,6,
  11. Said M. Sebti3,6 and
  12. Claudio Anasetti1,2,3
  1. 1Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA.
  2. 2Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.
  3. 3Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.
  4. 4Department of Hematopathology and Laboratory Medicine, Moffitt Cancer Center, Tampa, FL 33612, USA.
  5. 5Translational Research Core, Moffitt Cancer Center, Tampa, FL 33612, USA.
  6. 6Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.
  1. *Corresponding author. Email: brian.betts{at}moffitt.org

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