Research ArticleCancer

Anti–PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM

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Science Translational Medicine  21 Dec 2016:
Vol. 8, Issue 370, pp. 370ra180
DOI: 10.1126/scitranslmed.aag2942

Article Information

vol. 8 no. 370 370ra180

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication May 13, 2015
  • Resubmitted June 6, 2016
  • Accepted for publication September 27, 2016
  • .

Author Information

  1. Dimitrios Mathios1,*,
  2. Jennifer E. Kim1,*,
  3. Antonella Mangraviti1,
  4. Jillian Phallen1,2,
  5. Chul-Kee Park1,3,
  6. Christopher M. Jackson1,
  7. Tomas Garzon-Muvdi1,
  8. Eileen Kim1,
  9. Debebe Theodros1,
  10. Magdalena Polanczyk4,
  11. Allison M. Martin2,
  12. Ian Suk1,
  13. Xiaobu Ye1,
  14. Betty Tyler1,
  15. Chetan Bettegowda1,
  16. Henry Brem1,
  17. Drew M. Pardoll4 and
  18. Michael Lim1,
  1. 1Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  2. 2Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  3. 3Department of Neurosurgery, Seoul National University College of Medicine, Seoul 110-744, South Korea.
  4. 4Department of Cancer Immunology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  1. Corresponding author. Email: mlim3{at}jhmi.edu
    • * These authors contributed equally to this work.

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