Research ArticleAlzheimer’s Disease

Early changes in CSF sTREM2 in dominantly inherited Alzheimer’s disease occur after amyloid deposition and neuronal injury

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Science Translational Medicine  14 Dec 2016:
Vol. 8, Issue 369, pp. 369ra178
DOI: 10.1126/scitranslmed.aag1767

Article Information

vol. 8 no. 369 369ra178

PubMed: 
Print ISSN: 
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History: 
  • Received for publication May 24, 2016
  • Accepted for publication November 23, 2016
  • .

Author Information

  1. Marc Suárez-Calvet1,2,
  2. Miguel Ángel Araque Caballero3,
  3. Gernot Kleinberger2,4,
  4. Randall J. Bateman5,6,7,
  5. Anne M. Fagan5,6,7,
  6. John C. Morris5,6,7,
  7. Johannes Levin1,8,
  8. Adrian Danek1,8,
  9. Michael Ewers3,*,,
  10. Christian Haass1,2,4,*,,
  11. for the Dominantly Inherited Alzheimer Network
  1. 1German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany.
  2. 2Biomedical Center, Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
  3. 3Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany.
  4. 4Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  5. 5Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  6. 6Knight Alzheimer’s Disease Research Center, Washington University in St. Louis, St. Louis, MO 63110, USA.
  7. 7Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO 63110, USA.
  8. 8Department of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.
  1. Corresponding author. Email: christian.haass{at}mail03.med.uni-muenchen.de (C.H.); michael.ewers{at}med.uni-muenchen.de (M.E.)
    • * These authors contributed equally to this work.

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