Research ArticleCancer

PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation

See allHide authors and affiliations

Science Translational Medicine  14 Dec 2016:
Vol. 8, Issue 369, pp. 369ra175
DOI: 10.1126/scitranslmed.aae0348

Article Information

vol. 8 no. 369 369ra175

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 20, 2016
  • Resubmitted September 6, 2016
  • Accepted for publication October 5, 2016
  • .

Author Information

  1. Grace R. Anderson1,
  2. Suzanne E. Wardell1,
  3. Merve Cakir1,2,
  4. Lorin Crawford1,3,
  5. Jim C. Leeds1,
  6. Daniel P. Nussbaum1,4,
  7. Pallavi S. Shankar1,
  8. Ryan S. Soderquist1,
  9. Elizabeth M. Stein1,
  10. Jennifer P. Tingley1,
  11. Peter S. Winter1,5,
  12. Elizabeth K. Zieser-Misenheimer1,
  13. Holly M. Alley1,
  14. Alexander Yllanes1,
  15. Victoria Haney1,
  16. Kimberly L. Blackwell6,
  17. Shannon J. McCall7,
  18. Donald P. McDonnell1 and
  19. Kris C. Wood1,*
  1. 1Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA.
  2. 2Program in Computational Biology and Bioinformatics, Duke University, Durham, NC 27708, USA.
  3. 3Department of Statistical Science, Duke University, Durham, NC 27708, USA.
  4. 4Department of Surgery, Duke University, Durham, NC 27710, USA.
  5. 5Program in Genetics and Genomics, Duke University, Durham, NC 27710, USA.
  6. 6Department of Medicine/Oncology, Duke University, Durham, NC 27710, USA.
  7. 7Department of Pathology, Duke University, Durham, NC 27710, USA.
  1. *Corresponding author. Email: kris.wood{at}duke.edu

Altmetric

Article usage

Article usage: December 2016 to November 2019

AbstractFullPdf
Dec 20165555214526
Jan 2017100250102
Feb 20175854461
Mar 20172402725
Apr 20172152835
May 20171802217
Jun 20171492828
Jul 20171681320
Aug 20172121937
Sep 20171542225
Oct 20171341625
Nov 20171301322
Dec 2017901212
Jan 2018112718
Feb 201863812
Mar 20181052018
Apr 20181091121
May 2018971130
Jun 2018921815
Jul 201870710
Aug 201849128
Sep 2018441916
Oct 2018561810
Nov 2018851410
Dec 201862148
Jan 2019661216
Feb 201946178
Mar 2019311518
Apr 2019311723
May 2019281313
Jun 2019451417
Jul 201947179
Aug 201914109
Sep 201927187
Oct 2019371113
Nov 2019550