Reloadable multidrug capturing delivery system for targeted ischemic disease treatment

Jasmine P. J. Wu; Bill Cheng; Steve R. Roffler; David J. Lundy; Christopher Y. T. Yen; Peilin Chen; James J. Lai; Suzie H. Pun; Patrick S. Stayton; Patrick C. H. Hsieh

doi:10.1126/scitranslmed.aah6228

Research ArticleCardiovascular Disease

Reloadable multidrug capturing delivery system for targeted ischemic disease treatment

Jasmine P. J. Wu¹,
Bill Cheng¹,
Steve R. Roffler¹,²,*,
David J. Lundy¹,
Christopher Y. T. Yen¹,
Peilin Chen³,
James J. Lai⁴,
Suzie H. Pun⁴,
Patrick S. Stayton⁴ and
Patrick C. H. Hsieh¹,⁴,⁵,*

¹Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.
²Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
³Research Center for Applied Sciences, Academia Sinica, Taipei 115, Taiwan.
⁴Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.
⁵Institute of Medical Genomics and Proteomics and Department of Surgery, National Taiwan University and Hospital, Taipei 100, Taiwan.

↵*Corresponding author. Email: phsieh{at}ibms.sinica.edu.tw (P.C.H.H.); sroff{at}ibms.sinica.edu.tw (S.R.R.)

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Science Translational Medicine 16 Nov 2016:
Vol. 8, Issue 365, pp. 365ra160
DOI: 10.1126/scitranslmed.aah6228

Jasmine P. J. Wu

1Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.

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Bill Cheng

1Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.

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Steve R. Roffler

1Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.

2Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.

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For correspondence: phsieh@ibms.sinica.edu.tw sroff@ibms.sinica.edu.tw

David J. Lundy

1Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.

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Christopher Y. T. Yen

1Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.

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Peilin Chen

3Research Center for Applied Sciences, Academia Sinica, Taipei 115, Taiwan.

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James J. Lai

4Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

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Suzie H. Pun

4Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

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Patrick S. Stayton

4Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

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Patrick C. H. Hsieh

1Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.

4Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

5Institute of Medical Genomics and Proteomics and Department of Surgery, National Taiwan University and Hospital, Taipei 100, Taiwan.

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For correspondence: phsieh@ibms.sinica.edu.tw sroff@ibms.sinica.edu.tw

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Reloadable multidrug capturing delivery system for targeted ischemic disease treatment

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