Research ArticleAutoimmunity

Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors

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Science Translational Medicine  16 Nov 2016:
Vol. 8, Issue 365, pp. 365ra158
DOI: 10.1126/scitranslmed.aaf9418

Article Information

vol. 8 no. 365 365ra158

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 24, 2016
  • Accepted for publication September 29, 2016
  • .

Author Information

  1. Daniel F. Ortiz1,*,
  2. Jonathan C. Lansing1,*,
  3. Laura Rutitzky1,
  4. Elma Kurtagic1,
  5. Thomas Prod’homme1,
  6. Amit Choudhury1,
  7. Nathaniel Washburn1,
  8. Naveen Bhatnagar1,
  9. Christopher Beneduce1,
  10. Kimberly Holte1,
  11. Robert Prenovitz1,
  12. Matthew Child1,
  13. Jason Killough1,
  14. Steven Tyler1,
  15. Julia Brown1,
  16. Stephanie Nguyen1,
  17. Inessa Schwab2,
  18. Maurice Hains1,
  19. Robin Meccariello1,
  20. Lynn Markowitz1,
  21. Jing Wang1,
  22. Radouane Zouaoui1,
  23. Allison Simpson1,
  24. Birgit Schultes1,
  25. Ishan Capila1,
  26. Leona Ling1,
  27. Falk Nimmerjahn2,
  28. Anthony M. Manning1 and
  29. Carlos J. Bosques1,
  1. 1Momenta Pharmaceuticals, 675 West Kendall Street, Cambridge, MA 02142, USA.
  2. 2Department of Biology, Institute of Genetics, University of Erlangen-Nürnberg, 91058 Erlangen, Germany.
  1. Corresponding author. Email: cbosques{at}momentapharma.com
    • * These authors contributed equally to this work.

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