Research ArticleAutoimmunity

Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity

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Science Translational Medicine  02 Nov 2016:
Vol. 8, Issue 363, pp. 363ra149
DOI: 10.1126/scitranslmed.aag1974

Article Information

vol. 8 no. 363 363ra149

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication May 22, 2016
  • Accepted for publication October 14, 2016

Author Information

  1. Calliope A. Dendrou1,
  2. Adrian Cortes1,2,
  3. Lydia Shipman1,
  4. Hayley G. Evans1,
  5. Kathrine E. Attfield3,
  6. Luke Jostins2,
  7. Thomas Barber1,
  8. Gurman Kaur3,
  9. Subita Balaram Kuttikkatte3,
  10. Oliver A. Leach1,
  11. Christiane Desel1,
  12. Soren L. Faergeman1,4,
  13. Jane Cheeseman5,
  14. Matt J. Neville5,6,
  15. Stephen Sawcer7,
  16. Alastair Compston7,
  17. Adam R. Johnson8,
  18. Christine Everett8,
  19. John I. Bell9,
  20. Fredrik Karpe5,6,
  21. Mark Ultsch8,
  22. Charles Eigenbrot8,
  23. Gil McVean2 and
  24. Lars Fugger1,3,4,*
  1. 1Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, Division of Clinical Neurology, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.
  2. 2Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
  3. 3Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.
  4. 4Department of Clinical Medicine, Aarhus University Hospital, 8200 Aarhus N, Denmark.
  5. 5Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Oxford OX3 7LE, UK.
  6. 6National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals Trust, Churchill Hospital, Oxford OX3 7LE, UK.
  7. 7Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0QQ, UK.
  8. 8Structural Biology and Biochemical Pharmacology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  9. 9University of Oxford, Richard Doll Building, Roosevelt Drive, Oxford OX3 7DG, UK.
  1. *Corresponding author. Email: lars.fugger{at}imm.ox.ac.uk

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