02 November 2016
Vol 8, Issue 363
  • Contents

    • Research Articles

    • Reports

    • Editors' Choice

      • Stronger together

        Improved endothelial progenitor cell proliferation function supports hematopoietic stem cell proliferation after allogeneic stem cell transplant engraftment.

      • Caspase-2: Divide and conquer

        Preventing caspase-2 cleavage of tau blocks memory impairment in an animal model of Alzheimer’s disease.

      • Sleepy, leaky gut

        Chronic sleep disruption leads to alteration of gut microbiota, systemic and adipose tissue inflammation, and insulin resistance in mice.

About The Cover

Cover image expansion

ONLINE COVER A Broken Heart, Mended. Shown is an injured guinea pig heart successfully repaired with a living patch of tissue grown from human stem cells (Weinberger et al.). The patch contained stem cell–derived blood vessel and heart cells, which caused remuscularization of the injured area and improved pumping of the heart. [CREDIT: KAJA BRECKWOLDT, UNIVERSITY MEDICAL CENTER HAMBURG-EPPENDORF]