Research ArticleVECTOR CONTROL

Efficacy of the Olyset Duo net against insecticide-resistant mosquito vectors of malaria

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Science Translational Medicine  14 Sep 2016:
Vol. 8, Issue 356, pp. 356ra121
DOI: 10.1126/scitranslmed.aad3270

A net for all reasons

Long-lasting insecticide-treated mosquito nets are the most widely used intervention for preventing transmission of malaria by anopheline mosquitoes. Their effectiveness is threatened by the development of resistance to pyrethroid insecticides enabling the mosquito to survive contact with the net. Olyset Duo is a new type of bed net treated with pyrethroid and a new insecticide, pyriproxifen, that disrupts the maturation of eggs in the ovaries of blood-fed mosquitoes. Ngufor and colleagues evaluated the capacity of the Olyset Duo net to control pyrethroid-resistant mosquitoes in laboratory tests and under household conditions in West Africa. The Olyset Duo net killed more pyrethroid-resistant mosquitoes than did the standard pyrethroid net and also sterilized any mosquitoes that survived exposure to the net. By preventing mosquito reproduction, the new net has the potential to reduce mosquito populations and malaria transmission in areas of high pyrethroid resistance.

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