Research ArticleAntibiotics
Treatment of otitis media by transtympanic delivery of antibiotics
- Rong Yang1,
- Vishakha Sabharwal2,
- Obiajulu S. Okonkwo1,
- Nadya Shlykova2,
- Rong Tong1,*,
- Lily Yun Lin1,
- Weiping Wang1,
- Shutao Guo1,
- John J. Rosowski3,
- Stephen I. Pelton2 and
- Daniel S. Kohane1,†
- 1Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
- 2Division of Pediatric Infectious Diseases, Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston, MA 02118, USA.
- 3Department of Otology and Laryngology, Eaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA.
- ↵†Corresponding author. Email: daniel.kohane{at}childrens.harvard.edu
↵* Present address: Department of Chemical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
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Science Translational Medicine 14 Sep 2016:
Vol. 8, Issue 356, pp. 356ra120
DOI: 10.1126/scitranslmed.aaf4363
Vol. 8, Issue 356, pp. 356ra120
DOI: 10.1126/scitranslmed.aaf4363
Rong Yang
1Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
Vishakha Sabharwal
2Division of Pediatric Infectious Diseases, Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston, MA 02118, USA.
Obiajulu S. Okonkwo
1Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
Nadya Shlykova
2Division of Pediatric Infectious Diseases, Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston, MA 02118, USA.
Rong Tong
1Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
Lily Yun Lin
1Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
Weiping Wang
1Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
Shutao Guo
1Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
John J. Rosowski
3Department of Otology and Laryngology, Eaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA.
Stephen I. Pelton
2Division of Pediatric Infectious Diseases, Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston, MA 02118, USA.
Daniel S. Kohane
1Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
