Research ArticleCancer
Spatially selective depletion of tumor-associated regulatory T cells with near-infrared photoimmunotherapy
- Kazuhide Sato1,2,*,
- Noriko Sato1,*,
- Biying Xu3,
- Yuko Nakamura1,
- Tadanobu Nagaya1,
- Peter L. Choyke1,
- Yoshinori Hasegawa2 and
- Hisataka Kobayashi1,†
- 1Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892–1002, USA.
- 2Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
- 3Image Probe Development Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892–3372, USA.
- ↵†Corresponding author. Email: kobayash{at}mail.nih.gov
↵* These authors contributed equally to this work.
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Science Translational Medicine 17 Aug 2016:
Vol. 8, Issue 352, pp. 352ra110
DOI: 10.1126/scitranslmed.aaf6843
Vol. 8, Issue 352, pp. 352ra110
DOI: 10.1126/scitranslmed.aaf6843
Kazuhide Sato
1Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892–1002, USA.
2Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
Noriko Sato
1Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892–1002, USA.
Biying Xu
3Image Probe Development Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892–3372, USA.
Yuko Nakamura
1Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892–1002, USA.
Tadanobu Nagaya
1Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892–1002, USA.
Peter L. Choyke
1Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892–1002, USA.
Yoshinori Hasegawa
2Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
Hisataka Kobayashi
1Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892–1002, USA.
