Research ArticleNephropathy

Low α-defensin gene copy number increases the risk for IgA nephropathy and renal dysfunction

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Science Translational Medicine  29 Jun 2016:
Vol. 8, Issue 345, pp. 345ra88
DOI: 10.1126/scitranslmed.aaf2106

Article Information

vol. 8 no. 345 345ra88

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication January 8, 2016
  • Accepted for publication June 10, 2016
  • .

Author Information

  1. Zhen Ai1,2,*,
  2. Ming Li1,2,*,
  3. Wenting Liu1,2,*,
  4. Jia-Nee Foo3,
  5. Omniah Mansouri4,
  6. Peiran Yin1,2,
  7. Qian Zhou1,2,
  8. Xueqing Tang1,2,
  9. Xiuqing Dong1,2,
  10. Shaozhen Feng1,2,
  11. Ricong Xu1,2,
  12. Zhong Zhong1,2,
  13. Jian Chen5,
  14. Jianxin Wan6,
  15. Tanqi Lou7,
  16. Jianwen Yu1,2,
  17. Qin Zhou1,2,
  18. Jinjin Fan1,2,
  19. Haiping Mao1,2,
  20. Daniel Gale8,
  21. Jonathan Barratt9,
  22. John A. L. Armour4,
  23. Jianjun Liu3,10,11, and
  24. Xueqing Yu1,2,
  1. 1Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, China.
  2. 2Key Laboratory of Nephrology, Ministry of Health and Guangdong Province, Guangzhou, Guangdong 510080, China.
  3. 3Human Genetics, Genome Institute of Singapore, Singapore 138672, Singapore.
  4. 4School of Life Sciences, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK.
  5. 5Department of Nephrology, Fuzhou General Hospital of Nanjing Military Command, Fuzhou, Fujian 350025, China.
  6. 6Department of Nephrology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350005, China.
  7. 7Department of Nephrology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, China.
  8. 8University College London Centre for Nephrology, Royal Free Hospital, London NW3 2PF, UK.
  9. 9Department of Infection, Immunity and Inflammation, University of Leicester, Leicester LE1 9HN, UK.
  10. 10School of Biological Sciences, Anhui Medical University, Hefei, Anhui 230032, China.
  11. 11Saw Swee Hock School of Public Health, National University of Singapore, Singapore 119077, Singapore.
  1. Corresponding author. Email: yuxq{at}mail.sysu.edu.cn (X.Y.); liuj3{at}gis.a-star.edu.sg (J.L.)
    • * These authors contributed equally to this work.

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