Research ArticleParkinson’s Disease

α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease

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Science Translational Medicine  08 Jun 2016:
Vol. 8, Issue 342, pp. 342ra78
DOI: 10.1126/scitranslmed.aaf3634

Article Information

vol. 8 no. 342 342ra78

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication February 23, 2016
  • Accepted for publication May 17, 2016
  • .

Author Information

  1. Roberto Di Maio1,2,3,*,
  2. Paul J. Barrett1,2,*,
  3. Eric K. Hoffman1,2,
  4. Caitlyn W. Barrett1,2,
  5. Alevtina Zharikov1,2,4,
  6. Anupom Borah1,5,
  7. Xiaoping Hu1,2,
  8. Jennifer McCoy1,2,
  9. Charleen T. Chu1,6,
  10. Edward A. Burton1,2,4,
  11. Teresa G. Hastings1,2 and
  12. J. Timothy Greenamyre1,2,4,
  1. 1Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  2. 2Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  3. 3Ri.MED Foundation, Palermo, Italy.
  4. 4Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA.
  5. 5Department of Life Science and Bioinformatics, Assam University, Silchar 788011, India.
  6. 6Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  1. Corresponding author. Email: jgreena{at}pitt.edu
    • * These authors contributed equally to this work.

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