Research ArticleCardiovascular Disease

Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase

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Science Translational Medicine  25 May 2016:
Vol. 8, Issue 340, pp. 340ra74
DOI: 10.1126/scitranslmed.aac4296

Article Information

vol. 8 no. 340 340ra74

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication June 30, 2015
  • Accepted for publication April 22, 2016
  • .

Author Information

  1. Svetlana N. Reilly1,*,,
  2. Xing Liu1,*,
  3. Ricardo Carnicer1,
  4. Alice Recalde1,
  5. Anna Muszkiewicz2,
  6. Raja Jayaram1,
  7. Maria Cristina Carena1,
  8. Rohan Wijesurendra1,
  9. Matilde Stefanini1,
  10. Nicoletta C. Surdo1,
  11. Oliver Lomas1,
  12. Chandana Ratnatunga3,
  13. Rana Sayeed3,
  14. George Krasopoulos3,
  15. Timothy Rajakumar4,
  16. Alfonso Bueno-Orovio2,
  17. Sander Verheule5,
  18. Tudor A. Fulga4,
  19. Blanca Rodriguez2,
  20. Ulrich Schotten5 and
  21. Barbara Casadei1,*,
  1. 1Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.
  2. 2Department of Computer Science, University of Oxford, Oxford OX1 3QD, UK.
  3. 3Cardiothoracic Surgery, Oxford Heart Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK.
  4. 4Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, UK.
  5. 5Department of Physiology, University of Maastricht, 6211 LK Maastricht, Netherlands.
  1. Corresponding author. Email: barbara.casadei{at}cardiov.ox.ac.uk (B.C.); svetlana.reilly{at}cardiov.ox.ac.uk (S.N.R.)
  • * These authors contributed equally to this work.

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