Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice
1Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
2Weill Medical College of Cornell University, New York, NY 10065, USA.
3Adult BMT (Bone Marrow Transplant) Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
4Department of Clinical and Experimental Medicine, University of Perugia, Perugia 06135, Italy.
5Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
6Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
7Program in Immunology, Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
8Program in Dermatopathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
9Department of Pathology and Laboratory Medicine, New Jersey Medical School and Robert Wood Johnson Medical School, Rutgers University, Newark, NJ 08903, USA.
10Department of Medicine and Genetics, Stanford University, Stanford, CA 94143, USA.
11Infectious Disease Service, Lucille Castori Center for Microbes, Inflammation and Cancer, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
9Department of Pathology and Laboratory Medicine, New Jersey Medical School and Robert Wood Johnson Medical School, Rutgers University, Newark, NJ 08903, USA.
2Weill Medical College of Cornell University, New York, NY 10065, USA.
11Infectious Disease Service, Lucille Castori Center for Microbes, Inflammation and Cancer, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
1Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
2Weill Medical College of Cornell University, New York, NY 10065, USA.
11Infectious Disease Service, Lucille Castori Center for Microbes, Inflammation and Cancer, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
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By Yusuke Shono, Melissa D. Docampo, Jonathan U. Peled, Suelen M. Perobelli, Enrico Velardi, Jennifer J. Tsai, Ann E. Slingerland, Odette M. Smith, Lauren F. Young, Jyotsna Gupta, Sophia R. Lieberman, Hillary V. Jay, Katya F. Ahr, Kori A. Porosnicu Rodriguez, Ke Xu, Marco Calarfiore, Hendrik Poeck, Silvia Caballero, Sean M. Devlin, Franck Rapaport, Jarrod A. Dudakov, Alan M. Hanash, Boglarka Gyurkocza, George F. Murphy, Camilla Gomes, Chen Liu, Eli L. Moss, Shannon B. Falconer, Ami S. Bhatt, Ying Taur, Eric G. Pamer, Marcel R. M. van den Brink, Robert R. Jenq
Science Translational Medicine : 339ra71
Treating neutropenic fever with broad-spectrum antibiotics after allogeneic hematopoietic stem cell transplant is associated with an increase in graft-versus-host disease in mice and humans.
By Yusuke Shono, Melissa D. Docampo, Jonathan U. Peled, Suelen M. Perobelli, Enrico Velardi, Jennifer J. Tsai, Ann E. Slingerland, Odette M. Smith, Lauren F. Young, Jyotsna Gupta, Sophia R. Lieberman, Hillary V. Jay, Katya F. Ahr, Kori A. Porosnicu Rodriguez, Ke Xu, Marco Calarfiore, Hendrik Poeck, Silvia Caballero, Sean M. Devlin, Franck Rapaport, Jarrod A. Dudakov, Alan M. Hanash, Boglarka Gyurkocza, George F. Murphy, Camilla Gomes, Chen Liu, Eli L. Moss, Shannon B. Falconer, Ami S. Bhatt, Ying Taur, Eric G. Pamer, Marcel R. M. van den Brink, Robert R. Jenq
Science Translational Medicine : 339ra71
Treating neutropenic fever with broad-spectrum antibiotics after allogeneic hematopoietic stem cell transplant is associated with an increase in graft-versus-host disease in mice and humans.
