Research ArticleGenetics
Delayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndrome
- Zhantao Yang1,
- Siobán B. Keel1,
- Akiko Shimamura2,3,*,
- Li Liu1,
- Aaron T. Gerds2,†,
- Henry Y. Li4,
- Brent L. Wood1,
- Bart L. Scott2 and
- Janis L. Abkowitz1,‡
- 1University of Washington, Seattle, WA 98195, USA.
- 2Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
- 3Seattle Children’s Hospital, Seattle, WA 98105, USA.
- 4Polyclinic, Seattle, WA 98104, USA.
- ↵‡Corresponding author. Email: janabk{at}uw.edu
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Science Translational Medicine 11 May 2016:
Vol. 8, Issue 338, pp. 338ra67
DOI: 10.1126/scitranslmed.aaf3006
Vol. 8, Issue 338, pp. 338ra67
DOI: 10.1126/scitranslmed.aaf3006
Zhantao Yang
1University of Washington, Seattle, WA 98195, USA.
Siobán B. Keel
1University of Washington, Seattle, WA 98195, USA.
Akiko Shimamura
2Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
3Seattle Children’s Hospital, Seattle, WA 98105, USA.
Li Liu
1University of Washington, Seattle, WA 98195, USA.
Aaron T. Gerds
2Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Henry Y. Li
4Polyclinic, Seattle, WA 98104, USA.
Brent L. Wood
1University of Washington, Seattle, WA 98195, USA.
Bart L. Scott
2Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Janis L. Abkowitz
1University of Washington, Seattle, WA 98195, USA.