Delayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndrome

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  Delayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndrome

  By Zhantao Yang, Siobán B. Keel, Akiko Shimamura, Li Liu, Aaron T. Gerds, Henry Y. Li, Brent L. Wood, Bart L. Scott, Janis L. Abkowitz

  Science Translational Medicine11 May 2016 : 338ra67

  When heme synthesis exceeds globin synthesis, red blood cell differentiation fails, resulting in severe anemia.

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  Delayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndrome

  By Zhantao Yang, Siobán B. Keel, Akiko Shimamura, Li Liu, Aaron T. Gerds, Henry Y. Li, Brent L. Wood, Bart L. Scott, Janis L. Abkowitz

  Science Translational Medicine11 May 2016 : 338ra67

  When heme synthesis exceeds globin synthesis, red blood cell differentiation fails, resulting in severe anemia.

  • Supplementary Materials

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