Research ArticleInfectious Disease

IRF7 inhibition prevents destructive innate immunity—A target for nonantibiotic therapy of bacterial infections

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Science Translational Medicine  27 Apr 2016:
Vol. 8, Issue 336, pp. 336ra59
DOI: 10.1126/scitranslmed.aaf1156

Article Information

vol. 8 no. 336 336ra59

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication December 23, 2015
  • Accepted for publication March 8, 2016
  • .

Author Information

  1. Manoj Puthia1,*,
  2. Ines Ambite1,*,
  3. Caterina Cafaro1,
  4. Daniel Butler1,
  5. Yujing Huang1,
  6. Nataliya Lutay1,
  7. Gustav Rydström1,
  8. Birgitta Gullstrand2,
  9. Bhairavi Swaminathan3,
  10. Aftab Nadeem1,
  11. Björn Nilsson3,4 and
  12. Catharina Svanborg1,
  1. 1Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, 223 62 Lund, Sweden.
  2. 2Section of Rheumatology, Department of Clinical Sciences, Lund University and Skåne University Hospital, 221 85 Lund, Sweden.
  3. 3Division of Hematology and Transfusion Medicine, Institute of Laboratory Medicine, Lund University, 223 62 Lund, Sweden.
  4. 4Broad Institute, 7 Cambridge Center, Cambridge, MA 02142, USA.
  1. Corresponding author. Email: catharina.svanborg{at}med.lu.se
  • * These authors contributed equally to this work.

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