A research roadmap for next-generation sequencing informatics

Russ B. Altman; Snehit Prabhu; Arend Sidow; Justin M. Zook; Rachel Goldfeder; David Litwack; Euan Ashley; George Asimenos; Carlos D. Bustamante; Katherine Donigan; Kathleen M. Giacomini; Elaine Johansen; Natalia Khuri; Eunice Lee; Xueying Sharon Liang; Marc Salit; Omar Serang; Zivana Tezak; Dennis P. Wall; Elizabeth Mansfield; Taha Kass-Hout

doi:10.1126/scitranslmed.aaf7314

PerspectiveRegulatory Science

A research roadmap for next-generation sequencing informatics

Russ B. Altman¹,*,
Snehit Prabhu²,
Arend Sidow³,
Justin M. Zook⁴,¹¹,
Rachel Goldfeder⁵,
David Litwack⁶,
Euan Ashley⁷,
George Asimenos⁸,
Carlos D. Bustamante²,
Katherine Donigan⁶,
Kathleen M. Giacomini⁹,
Elaine Johansen⁶,
Natalia Khuri¹⁰,
Eunice Lee⁶,
Xueying Sharon Liang⁶,
Marc Salit⁴,¹⁰,¹¹,
Omar Serang⁸,
Zivana Tezak⁶,
Dennis P. Wall¹²,
Elizabeth Mansfield⁶ and
Taha Kass-Hout⁶

¹Bioengineering, Genetics, and Medicine, Stanford University, Stanford, CA 94305, USA.
²Biomedical Data Science and Genetics, Stanford University, Stanford, CA 94305, USA.
³Pathology and Genetics, Stanford University, Stanford, CA 94305, USA.
⁴Material Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA.
⁵Biomedical Informatics, Stanford University, Stanford, CA 94305, USA.
⁶Food and Drug Administration, Silver Spring, MD 20993, USA.
⁷Medicine, Genetics, and Pathology, Stanford University, Stanford, CA 94305, USA.
⁸DNAnexus, Mountain View, CA 94040, USA.
⁹Bioengineering and Therapeutic Sciences, University of California at San Francisco, San Francisco, CA 94143, USA.
¹⁰Bioengineering, Stanford University, Stanford, CA 94305, USA.
¹¹Material Measurement Laboratory, National Institute of Standards and Technology, Stanford University, Stanford, CA 94305, USA.
¹²Systems Medicine and Psychiatry, Stanford University, Stanford, CA 94305, USA.

↵*Corresponding author. E-mail: russ.altman{at}stanford.edu

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Science Translational Medicine 20 Apr 2016:
Vol. 8, Issue 335, pp. 335ps10
DOI: 10.1126/scitranslmed.aaf7314

Russ B. Altman

Bioengineering, Genetics, and Medicine, Stanford University, Stanford, CA 94305, USA.

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For correspondence: russ.altman@stanford.edu

Snehit Prabhu

Biomedical Data Science and Genetics, Stanford University, Stanford, CA 94305, USA.

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Arend Sidow

Pathology and Genetics, Stanford University, Stanford, CA 94305, USA.

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Justin M. Zook

Material Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA.

Material Measurement Laboratory, National Institute of Standards and Technology, Stanford University, Stanford, CA 94305, USA.

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Rachel Goldfeder

Biomedical Informatics, Stanford University, Stanford, CA 94305, USA.

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David Litwack

Food and Drug Administration, Silver Spring, MD 20993, USA.

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Euan Ashley

Medicine, Genetics, and Pathology, Stanford University, Stanford, CA 94305, USA.

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George Asimenos

DNAnexus, Mountain View, CA 94040, USA.

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Carlos D. Bustamante

Biomedical Data Science and Genetics, Stanford University, Stanford, CA 94305, USA.

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Katherine Donigan

Food and Drug Administration, Silver Spring, MD 20993, USA.

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Kathleen M. Giacomini

Bioengineering and Therapeutic Sciences, University of California at San Francisco, San Francisco, CA 94143, USA.

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Elaine Johansen

Food and Drug Administration, Silver Spring, MD 20993, USA.

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Natalia Khuri

Bioengineering, Stanford University, Stanford, CA 94305, USA.

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Eunice Lee

Food and Drug Administration, Silver Spring, MD 20993, USA.

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Xueying Sharon Liang

Food and Drug Administration, Silver Spring, MD 20993, USA.

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Marc Salit

Material Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA.

Bioengineering, Stanford University, Stanford, CA 94305, USA.

Material Measurement Laboratory, National Institute of Standards and Technology, Stanford University, Stanford, CA 94305, USA.

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Omar Serang

DNAnexus, Mountain View, CA 94040, USA.

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Zivana Tezak

Food and Drug Administration, Silver Spring, MD 20993, USA.

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Dennis P. Wall

Systems Medicine and Psychiatry, Stanford University, Stanford, CA 94305, USA.

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Elizabeth Mansfield

Food and Drug Administration, Silver Spring, MD 20993, USA.

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Taha Kass-Hout

Food and Drug Administration, Silver Spring, MD 20993, USA.

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