Research ArticleCancer

Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence

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Science Translational Medicine  13 Apr 2016:
Vol. 8, Issue 334, pp. 334ra53
DOI: 10.1126/scitranslmed.aad3001

Article Information

vol. 8 no. 334 334ra53

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication August 24, 2015
  • Accepted for publication March 16, 2016
  • .

Author Information

  1. Justin M. Balko1,2,3,*,,
  2. Luis J. Schwarz1,,
  3. Na Luo1,
  4. Mónica V. Estrada3,4,
  5. Jennifer M. Giltnane3,4,,
  6. Daniel Dávila-González5,
  7. Kai Wang6,
  8. Violeta Sánchez1,
  9. Phillip T. Dean1,
  10. Susan E. Combs7,
  11. Donna Hicks2,
  12. Joseph A. Pinto8,
  13. Melissa D. Landis5,
  14. Franco D. Doimi9,
  15. Roman Yelensky6,§,
  16. Vincent A. Miller6,
  17. Phillip J. Stephens6,
  18. David L. Rimm7,
  19. Henry Gómez9,
  20. Jenny C. Chang5,
  21. Melinda E. Sanders3,4,
  22. Rebecca S. Cook2,3 and
  23. Carlos L. Arteaga1,2,3,*
  1. 1Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
  2. 2Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA.
  3. 3Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA.
  4. 4Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232, USA.
  5. 5Houston Methodist Cancer Center, Houston, TX 77030, USA.
  6. 6Foundation Medicine, Cambridge, MA 02142, USA.
  7. 7Departments of Pathology and Medicine, Yale University, New Haven, CT 06520, USA.
  8. 8Oncosalud, Lima 41, Perú.
  9. 9Instituto Nacional de Enfermedades Neoplásicas (INEN), Lima 34, Perú.
  1. *Corresponding author. E-mail: carlos.arteaga{at}vanderbilt.edu (C.L.A.); justin.balko{at}vanderbilt.edu (J.M.B.)
  • These authors contributed equally to this work.

  • Present address: Genentech, San Francisco, CA 94080, USA.

  • § Present address: Gritstone Oncology, Cambridge, MA 02142, USA.

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