06 April 2016
Vol 8, Issue 333

About The Cover

Cover image expansion

ONLINE COVER Personalized Dosing. Keeping track of drug doses for patients on complicated regimens is no trivial task. To limit the educated guesswork and impart tighter control over the effects of multiple drugs, Zarrinpar and colleagues devised a mathematical approach that used drug concentration as an input and trough level in the blood as the output. The authors compared their equation against standard physician-guided care in a pilot study of eight patients who were on immunosuppressants after liver transplants. [CREDIT: Zarrinpar et al., SCIENCE TRANSLATIONAL MEDICINE]