Research ArticleAutoimmunity
Restoring oxidant signaling suppresses proarthritogenic T cell effector functions in rheumatoid arthritis
- Zhen Yang1,
- Yi Shen1,
- Hisashi Oishi1,*,
- Eric L. Matteson2,
- Lu Tian3,
- Jörg J. Goronzy1 and
- Cornelia M. Weyand1,†
- 1Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
- 2Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
- 3Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305, USA.
- ↵†Corresponding author. E-mail: cweyand{at}stanford.edu
↵* Present address: Department of Anatomy and Embryology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
See allHide authors and affiliations
Science Translational Medicine 23 Mar 2016:
Vol. 8, Issue 331, pp. 331ra38
DOI: 10.1126/scitranslmed.aad7151
Vol. 8, Issue 331, pp. 331ra38
DOI: 10.1126/scitranslmed.aad7151
Zhen Yang
1Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Yi Shen
1Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Hisashi Oishi
1Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Eric L. Matteson
2Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Lu Tian
3Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305, USA.
Jörg J. Goronzy
1Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Cornelia M. Weyand
1Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.