Research ArticleInfectious Disease
The live attenuated dengue vaccine TV003 elicits complete protection against dengue in a human challenge model
- Beth D. Kirkpatrick1,*,
- Stephen S. Whitehead2,*,
- Kristen K. Pierce1,
- Cecilia M. Tibery3,
- Palmtama L. Grier3,
- Noreen A. Hynes4,
- Catherine J. Larsson1,
- Beulah P. Sabundayo3,
- Kawsar R. Talaat3,
- Anna Janiak3,
- Marya P. Carmolli1,
- Catherine J. Luke4,
- Sean A. Diehl1 and
- Anna P. Durbin3,†
- 1Vaccine Testing Center, Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05401, USA.
- 2National Institutes of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
- 3Center for Immunization Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
- 4Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
- ↵†Corresponding author. E-mail: adurbin1{at}jhu.edu
↵* Co-first authors.
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Science Translational Medicine 16 Mar 2016:
Vol. 8, Issue 330, pp. 330ra36
DOI: 10.1126/scitranslmed.aaf1517
Vol. 8, Issue 330, pp. 330ra36
DOI: 10.1126/scitranslmed.aaf1517
Beth D. Kirkpatrick
1Vaccine Testing Center, Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05401, USA.
Stephen S. Whitehead
2National Institutes of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Kristen K. Pierce
1Vaccine Testing Center, Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05401, USA.
Cecilia M. Tibery
3Center for Immunization Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Palmtama L. Grier
3Center for Immunization Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Noreen A. Hynes
4Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Catherine J. Larsson
1Vaccine Testing Center, Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05401, USA.
Beulah P. Sabundayo
3Center for Immunization Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Kawsar R. Talaat
3Center for Immunization Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Anna Janiak
3Center for Immunization Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Marya P. Carmolli
1Vaccine Testing Center, Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05401, USA.
Catherine J. Luke
4Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Sean A. Diehl
1Vaccine Testing Center, Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05401, USA.
Anna P. Durbin
3Center for Immunization Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.