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PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

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Science Translational Medicine  02 Mar 2016:
Vol. 8, Issue 328, pp. 328rv4
DOI: 10.1126/scitranslmed.aad7118

Article Information

vol. 8 no. 328 328rv4

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History: 
  • Received for publication October 23, 2015
  • Accepted for publication January 20, 2016
  • .

Author Information

  1. Weiping Zou1,*,
  2. Jedd D. Wolchok2,* and
  3. Lieping Chen3,*
  1. 1Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  2. 2Department of Medicine and the Ludwig Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  3. 3Department of Immunobiology, Yale University School of Medicine, New Haven CT 06519, USA.
  1. *Corresponding author. E-mail: wzou{at}med.umich.edu (W.Z.); wolchokj{at}mskcc.org (J.D.W.); lieping.chen{at}yale.edu (L.C.)

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