24 February 2016
Vol 8, Issue 327

About The Cover

Cover image expansion

ONLINE COVER Protecting Against Metastasis. Notre Dame de Paris gargoyles guard over the city of Paris to frighten off and protect from any evil or harmful spirits. In this issue of Science Translational Medicine, Mlecnik et al. describe the protective role of cytotoxic immune infiltrate, Immunoscore, and lymphatic vessels against metastatic invasion in human cancer. These results support the use of T cell based immunotherapy at early stage disease. [CREDIT: Julian Elliott/robertharding/Corbis]