Chronic administration of an HDAC inhibitor treats both neurological and systemic Niemann-Pick type C disease in a mouse model | Science Translational Medicine

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Article Information

vol. 8 no. 326 326ra23

DOI:

https://doi.org/10.1126/scitranslmed.aad9407

PubMed:

Published By:

American Association for the Advancement of Science

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Online ISSN:

History:

Received for publication November 24, 2015
Accepted for publication January 28, 2016
.

Copyright & Usage:

Copyright © 2016, American Association for the Advancement of Science

Author Information

Md. Suhail Alam¹,²,
Michelle Getz¹,² and
Kasturi Haldar¹,²,*

¹Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA.
²Department of Biological Sciences, University of Notre Dame, 103 Galvin Life Sciences, Notre Dame, IN 46556, USA.

↵*Corresponding author. E-mail: khaldar{at}nd.edu

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Science Translational Medicine: 8 (326)

Science Translational Medicine

Vol 8, Issue 326
17 February 2016

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Chronic administration of an HDAC inhibitor treats both neurological and systemic Niemann-Pick type C disease in a mouse model

By Md. Suhail Alam, Michelle Getz, Kasturi Haldar

Science Translational Medicine17 Feb 2016 : 326ra23

Integrated, long-term HDAC inhibitor therapy treats neurodegeneration and systemic disease in a mouse model of Niemann-Pick type C.

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Chronic administration of an HDAC inhibitor treats both neurological and systemic Niemann-Pick type C disease in a mouse model

By Md. Suhail Alam, Michelle Getz, Kasturi Haldar

Science Translational Medicine17 Feb 2016 : 326ra23

Integrated, long-term HDAC inhibitor therapy treats neurodegeneration and systemic disease in a mouse model of Niemann-Pick type C.

Supplementary Materials
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