Research ArticleNanomedicine

Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo

See allHide authors and affiliations

Science Translational Medicine  10 Feb 2016:
Vol. 8, Issue 325, pp. 325ra17
DOI: 10.1126/scitranslmed.aad2355

Article Information

vol. 8 no. 325 325ra17

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication August 14, 2015
  • Accepted for publication January 8, 2016
  • .

Author Information

  1. Susan Ashton1,
  2. Young Ho Song2,
  3. Jim Nolan2,
  4. Elaine Cadogan1,
  5. Jim Murray3,
  6. Rajesh Odedra1,
  7. John Foster4,
  8. Peter A. Hall4,
  9. Susan Low2,
  10. Paula Taylor1,
  11. Rebecca Ellston1,
  12. Urszula M. Polanska1,
  13. Joanne Wilson1,
  14. Colin Howes1,
  15. Aaron Smith1,
  16. Richard J. A. Goodwin4,
  17. John G. Swales4,
  18. Nicole Strittmatter5,
  19. Zoltán Takáts5,
  20. Anna Nilsson6,
  21. Per Andren6,
  22. Dawn Trueman1,
  23. Mike Walker1,
  24. Corinne L. Reimer7,
  25. Greg Troiano2,
  26. Donald Parsons2,
  27. David De Witt2,
  28. Marianne Ashford3,
  29. Jeff Hrkach2,
  30. Stephen Zale2,*,
  31. Philip J. Jewsbury1,* and
  32. Simon T. Barry1,*
  1. 1Oncology iMED, AstraZeneca, Macclesfield, Cheshire SK10 4TG, UK.
  2. 2BIND Therapeutics, 325 Vassar Street, Cambridge, MA 02139, USA.
  3. 3Pharmaceutical Development, AstraZeneca, Macclesfield, Cheshire SK10 2NX, UK.
  4. 4Drug Safety and Metabolism, Innovative Medicines, AstraZeneca R&D, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK.
  5. 5Department of Surgery and Cancer, Imperial College, London SW7 2AZ, UK.
  6. 6Biomolecular Imaging and Proteomics, National Center for Mass Spectrometry Imaging, Uppsala University, Uppsala 751 05, Sweden.
  7. 7Oncology iMED, AstraZeneca, Gatehouse Park, Waltham, Boston 02451, USA.
  1. *Corresponding author. E-mail: simon.t.barry{at}astrazeneca.com (S.T.B.); philip.jewsbury{at}astrazeneca.com (P.J.J.); szale{at}bindtherapeutics.com (S.Z.)

Altmetric

Article usage

Article usage: February 2016 to October 2020

AbstractFullPdf
Feb 20165855529941
Mar 2016766109152
Apr 2016731150267
May 2016569110137
Jun 201643592119
Jul 20163717089
Aug 20163715378
Sep 20162342358
Oct 201660710596
Nov 20162854039
Dec 20163343543
Jan 20172913542
Feb 20174303756
Mar 20178054360
Apr 20175472640
May 20177373555
Jun 20176932342
Jul 20173832123
Aug 20172072144
Sep 20171873043
Oct 20172232223
Nov 20172403435
Dec 20171942344
Jan 20182144042
Feb 20181943834
Mar 20181985849
Apr 20182225037
May 20182074231
Jun 20182024144
Jul 20181673330
Aug 2018992519
Sep 20181123528
Oct 20181114935
Nov 20181425428
Dec 20181254412
Jan 20191404538
Feb 20191015022
Mar 20191085241
Apr 2019924325
May 20191034429
Jun 20191114230
Jul 2019804525
Aug 2019673120
Sep 2019532320
Oct 2019683322
Nov 2019683524
Dec 2019692014
Jan 202054259
Feb 2020602616
Mar 2020691736
Apr 2020723815
May 2020904936
Jun 2020651517
Jul 2020553012
Aug 2020753314
Sep 2020832519
Oct 202080219

Stay Connected to Science Translational Medicine