Research ArticleCIRCADIAN RHYTHM

Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival

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Science Translational Medicine  03 Feb 2016:
Vol. 8, Issue 324, pp. 324ra16
DOI: 10.1126/scitranslmed.aad3305

Article Information

vol. 8 no. 324 324ra16

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication August 28, 2015
  • Accepted for publication December 29, 2015
  • .

Author Information

  1. Guangrui Yang1,*,
  2. Lihong Chen1,*,
  3. Gregory R. Grant1,2,
  4. Georgios Paschos1,
  5. Wen-Liang Song1,
  6. Erik S. Musiek3,
  7. Vivian Lee4,
  8. Sarah C. McLoughlin1,
  9. Tilo Grosser1,
  10. George Cotsarelis5 and
  11. Garret A. FitzGerald1,
  1. 1The Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  2. 2Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA.
  3. 3Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.
  4. 4Department of Ophthalmology, University of Pennsylvania Scheie Eye Institute, Philadelphia, PA 19104, USA.
  5. 5Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
  1. Corresponding author. E-mail: garret{at}upenn.edu
    • * These authors contributed equally to this work.

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