Research ArticleMetabolism
Complex effects of inhibiting hepatic apolipoprotein B100 synthesis in humans
- Gissette Reyes-Soffer1,*,
- Byoung Moon1,
- Antonio Hernandez-Ono1,
- Marija Dionizovik-Dimanovski1,
- Jhonsua Jimenez1,
- Joseph Obunike2,
- Tiffany Thomas1,
- Colleen Ngai1,
- Nelson Fontanez1,
- Daniel S. Donovan1,
- Wahida Karmally1,
- Stephen Holleran1,
- Rajasekhar Ramakrishnan1,
- Robert S. Mittleman3† and
- Henry N. Ginsberg1,*
- 1Columbia University College of Physicians and Surgeons, 630 West 168th Street, New York, NY 10032, USA.
- 2Biological Sciences Department, New York City College of Technology, 300 Jay Street, Brooklyn, NY 11201, USA.
- 3Sanofi-Genzyme, 500 Kendall Street, Cambridge, MA 02142, USA.
- ↵*Corresponding author. E-mail: gr2104{at}cumc.columbia.edu (G.R.-S.); hng1{at}cumc.columbia.edu (H.N.G.)
↵† Present address: Ironwood Pharmaceuticals, 301 Binney Street, Cambridge, MA 02142, USA.
See allHide authors and affiliations
Science Translational Medicine 27 Jan 2016:
Vol. 8, Issue 323, pp. 323ra12
DOI: 10.1126/scitranslmed.aad2195
