Research ArticleInfectious Disease

CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival

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Science Translational Medicine  20 Jan 2016:
Vol. 8, Issue 322, pp. 322ra10
DOI: 10.1126/scitranslmed.aac7718

Article Information

vol. 8 no. 322 322ra10

PubMed: 
Print ISSN: 
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History: 
  • Received for publication June 11, 2015
  • Accepted for publication December 8, 2015
  • .

Author Information

  1. Muthulekha Swamydas1,*,
  2. Ji-Liang Gao2,*,
  3. Timothy J. Break1,
  4. Melissa D. Johnson3,
  5. Martin Jaeger4,
  6. Carlos A. Rodriguez5,
  7. Jean K. Lim5,
  8. Nathaniel M. Green1,
  9. Amanda L. Collar1,
  10. Brett G. Fischer1,2,
  11. Chyi-Chia Richard Lee6,
  12. John R. Perfect3,
  13. Barbara D. Alexander3,
  14. Bart-Jan Kullberg4,
  15. Mihai G. Netea4,
  16. Philip M. Murphy2 and
  17. Michail S. Lionakis1,
  1. 1Fungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  2. 2Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA.
  3. 3Duke University School of Medicine, Durham, NC 27708, USA.
  4. 4Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen 6500HB, Netherlands.
  5. 5Department of Microbiology, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
  6. 6Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  1. Corresponding author. E-mail: lionakism{at}niaid.nih.gov
    • * These authors contributed equally to this work.

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