Research ArticleImmunotherapy

Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory

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Science Translational Medicine  09 Dec 2015:
Vol. 7, Issue 317, pp. 317ra198
DOI: 10.1126/scitranslmed.aac8265

Article Information

vol. 7 no. 317 317ra198

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication June 24, 2015
  • Accepted for publication November 11, 2015
  • .

Author Information

  1. Giacomo Oliveira1,2,
  2. Eliana Ruggiero1,3,
  3. Maria Teresa Lupo Stanghellini4,
  4. Nicoletta Cieri1,*,
  5. Mattia D’Agostino1,2,
  6. Raffaele Fronza3,
  7. Christina Lulay3,
  8. Francesca Dionisio5,
  9. Sara Mastaglio1,4,
  10. Raffaella Greco4,
  11. Jacopo Peccatori4,
  12. Alessandro Aiuti5,
  13. Alessandro Ambrosi2,
  14. Luca Biasco5,
  15. Attilio Bondanza4,6,
  16. Antonio Lambiase7,
  17. Catia Traversari7,
  18. Luca Vago4,8,
  19. Christof von Kalle3,
  20. Manfred Schmidt3,
  21. Claudio Bordignon2,7,
  22. Fabio Ciceri2,4,8 and
  23. Chiara Bonini1,2,
  1. 1Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, Program in Immunology and Bio-Immunotherapy of Cancer (PIBIC), San Raffaele Scientific Institute, Milan 20132, Italy.
  2. 2Vita-Salute San Raffaele University, Milan 20132, Italy.
  3. 3Department of Translational Oncology, National Center for Tumor Diseases and German Cancer Research Center, Heidelberg 69120, Germany.
  4. 4Hematology and Bone Marrow Transplantation Unit, San Raffaele Scientific Institute, Milan 20132, Italy.
  5. 5Telethon Institute for Gene Therapy (HSR-TIGET), San Raffaele Scientific Institute, Milan 20132, Italy.
  6. 6Innovative Immunotherapies Unit, Division of Immunology, Transplantation and Infectious Diseases, PIBIC, San Raffaele Scientific Institute, Milan 20132, Italy.
  7. 7MolMed S.p.A, Milan 20132, Italy.
  8. 8Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Milan 20132, Italy.
  1. Corresponding author. E-mail: bonini.chiara{at}hsr.it
  • * Present address: University of Milan, Milan 20132, Italy.

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