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Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer

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Science Translational Medicine  18 Nov 2015:
Vol. 7, Issue 314, pp. 314ra186
DOI: 10.1126/scitranslmed.aac7433

Article Information

vol. 7 no. 314 314ra186

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication June 5, 2015
  • Accepted for publication September 28, 2015
  • .

Author Information

  1. Melissa R. Junttila*,
  2. Weiguang Mao,
  3. Xi Wang,
  4. Bu-Er Wang,
  5. Thinh Pham,
  6. John Flygare,
  7. Shang-Fan Yu,
  8. Sharon Yee,
  9. David Goldenberg,
  10. Carter Fields,
  11. Jeffrey Eastham-Anderson,
  12. Mallika Singh,
  13. Rajesh Vij,
  14. Jo-Anne Hongo,
  15. Ron Firestein,
  16. Melissa Schutten,
  17. Kelly Flagella§,
  18. Paul Polakis and
  19. Andrew G. Polson*
  1. Research and Early Development, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  1. *Corresponding author. E-mail: polson{at}gene.com (A.G.P.); junttila.melissa{at}gene.com (M.R.J.)
    • Present address: Patronus Therapeutics Inc., San Francisco, CA 94080, USA.

    • Present address: Hudson Institute of Medical Research, Clayton, Victoria 3168, Australia.

    • § Present address: BioMarin Pharmaceutical Inc., Novato, CA 94949, USA.

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