Research ArticleHuman Immunology

A validated gene regulatory network and GWAS identifies early regulators of T cell–associated diseases

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Science Translational Medicine  11 Nov 2015:
Vol. 7, Issue 313, pp. 313ra178
DOI: 10.1126/scitranslmed.aad2722

Article Information

vol. 7 no. 313 313ra178

PubMed: 
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History: 
  • Received for publication August 20, 2015
  • Accepted for publication October 1, 2015

Author Information

  1. Mika Gustafsson1,2,*,,
  2. Danuta R. Gawel1,,
  3. Lars Alfredsson3,
  4. Sergio Baranzini4,
  5. Janne Björkander5,
  6. Robert Blomgran6,
  7. Sandra Hellberg7,
  8. Daniel Eklund8,
  9. Jan Ernerudh7,8,
  10. Ingrid Kockum9,
  11. Aelita Konstantinell1,10,
  12. Riita Lahesmaa11,
  13. Antonio Lentini1,
  14. H. Robert I. Liljenström1,
  15. Lina Mattson1,
  16. Andreas Matussek5,
  17. Johan Mellergård12,
  18. Melissa Mendez13,
  19. Tomas Olsson9,
  20. Miguel A. Pujana14,
  21. Omid Rasool11,
  22. Jordi Serra-Musach14,
  23. Margaretha Stenmarker5,
  24. Subhash Tripathi11,
  25. Miro Viitala11,
  26. Hui Wang1,15,
  27. Huan Zhang1,
  28. Colm E. Nestor1, and
  29. Mikael Benson1,*,
  1. 1The Centre for Individualised Medicine, Department of Clinical and Experimental Medicine, Division of Pediatrics, Linköping University, SE-581 83 Linköping, Sweden.
  2. 2Bioinformatics, Department of Physics, Chemistry, and Biology, Linköping University, SE-581 83 Linköping, Sweden.
  3. 3Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Solna, Sweden.
  4. 4Department of Neurology, University of California, San Francisco, CA 94158, USA.
  5. 5Futurum-Academy for Health and Care, County Council of Jönköping, SE-551 85 Jönköping, Sweden.
  6. 6Department of Clinical and Experimental Medicine, Division of Microbiology and Molecular Medicine, Linköping University, SE-581 83 Linköping, Sweden.
  7. 7Department of Clinical and Experimental Medicine, Division of Clinical Immunology, Unit of Autoimmunity and Immune Regulation, Linköping University, SE-581 83 Linköping, Sweden.
  8. 8Department of Clinical Immunology and Transfusion Medicine, Linköping University, SE-581 83 Linköping, Sweden.
  9. 9Department of Clinical Neurosciences, Karolinska Institutet and Centrum for Molecular Medicine, SE-171 77 Stockholm, Sweden.
  10. 10Department of Medical Biology, The Arctic University of Norway, NO-9037 Tromsø, Norway.
  11. 11Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, FI-20520 Turku, Finland.
  12. 12Department of Neurology and Department of Clinical and Experimental Medicine, Linköping University, SE-581 83 Linköping, Sweden.
  13. 13Laboratorio de Investigación en Enfermedades Infecciosas, LID, Universidad Peruana Cayetano Heredia, Lima PE-15102, Peru.
  14. 14Program Against Cancer Therapeutic Resistance (ProCURE), Cancer and Systems Biology Unit, Catalan Institute of Oncology, IDIBELL, L’Hospitalet del Llobregat, ES-08908 Barcelona, Spain.
  15. 15Department of Immunology, MD Anderson Cancer Center, Houston, TX 77030, USA.
  1. *Corresponding author. E-mail: mika.gustafsson{at}liu.se (M.G.); mikael.benson{at}liu.se (M.B.)
    • These authors contributed equally to this work and should be regarded as shared first or last authors, respectively.

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