Research ArticleInfectious Disease

A gene deletion that up-regulates viral gene expression yields an attenuated RSV vaccine with improved antibody responses in children

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Science Translational Medicine  04 Nov 2015:
Vol. 7, Issue 312, pp. 312ra175
DOI: 10.1126/scitranslmed.aac8463

Article Information

vol. 7 no. 312 312ra175

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication June 22, 2015
  • Accepted for publication August 27, 2015
  • .

Author Information

  1. Ruth A. Karron1,*,
  2. Cindy Luongo2,
  3. Bhagvanji Thumar1,
  4. Karen M. Loehr1,
  5. Janet A. Englund3,
  6. Peter L. Collins2 and
  7. Ursula J. Buchholz2
  1. 1Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
  2. 2RNA Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy, Immunology, and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  3. 3Seattle Children’s Research Institute, University of Washington, Seattle, WA 98101, USA.
  1. *Corresponding author. E-mail: rkarron{at}jhu.edu

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