Research ArticleImmunotherapy
IL-2Rα mediates temporal regulation of IL-2 signaling and enhances immunotherapy
- Ee W. Su1,*,
- Caitlin J. Moore1,*,
- Samantha Suriano1,
- Christopher Bryce Johnson1,
- Neizel Songalia1,
- Alicia Patterson1,
- Daniel J. Neitzke1,
- Kristina Andrijauskaite1,
- Elizabeth Garrett-Mayer2,
- Shikhar Mehrotra1,
- Chrystal M. Paulos3,
- Andrew L. Doedens4,
- Ananda W. Goldrath4,
- Zihai Li3,
- David J. Cole1 and
- Mark P. Rubinstein1,3,†
- 1Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
- 2Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC 29425, USA.
- 3Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA.
- 4Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
- ↵†Corresponding author. E-mail: markrubinstein{at}musc.edu
↵* These authors contributed equally to this work.
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Science Translational Medicine 28 Oct 2015:
Vol. 7, Issue 311, pp. 311ra170
DOI: 10.1126/scitranslmed.aac8155
Vol. 7, Issue 311, pp. 311ra170
DOI: 10.1126/scitranslmed.aac8155
Ee W. Su
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Caitlin J. Moore
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Samantha Suriano
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Christopher Bryce Johnson
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Neizel Songalia
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Alicia Patterson
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Daniel J. Neitzke
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Kristina Andrijauskaite
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Elizabeth Garrett-Mayer
Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC 29425, USA.
Shikhar Mehrotra
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Chrystal M. Paulos
Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA.
Andrew L. Doedens
Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
Ananda W. Goldrath
Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
Zihai Li
Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA.
David J. Cole
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Mark P. Rubinstein
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA.
