Smooth muscle cell progenitors are primed to muscularize in pulmonary hypertension

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  Smooth muscle cell progenitors are primed to muscularize in pulmonary hypertension

  By Abdul Q. Sheikh, Ashish Misra, Ivan O. Rosas, Ralf H. Adams, Daniel M. Greif

  Science Translational Medicine07 Oct 2015 : 308ra159

  During the onset of pulmonary hypertension, a single specialized preexisting smooth muscle cell located at each muscularized-unmuscularized pulmonary arteriole border migrates distally and clonally expands, giving rise to the pathological distal arteriole smooth muscle.

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  Smooth muscle cell progenitors are primed to muscularize in pulmonary hypertension

  By Abdul Q. Sheikh, Ashish Misra, Ivan O. Rosas, Ralf H. Adams, Daniel M. Greif

  Science Translational Medicine07 Oct 2015 : 308ra159

  During the onset of pulmonary hypertension, a single specialized preexisting smooth muscle cell located at each muscularized-unmuscularized pulmonary arteriole border migrates distally and clonally expands, giving rise to the pathological distal arteriole smooth muscle.

  • Supplementary Materials

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