07 October 2015
Vol 7, Issue 308

About The Cover

Cover image expansion

ONLINE COVER Best Friends Lead the Way. Two determined dogs guide their human across a wooden bridge, no doubt eager to meet up with their buddies. In the same way, selected coteries of companion animals—those with naturally occurring genetic diseases that resemble human conditions—might forge an improved translational path toward human therapeutics by providing a developmental bridge between preclinical disease models in laboratory animals and clinical trials in human subjects. Veterinary clinical trials have the potential to provide more reliable information on the efficacy and safety of therapeutics in human subjects. In this issue, Kol et al. discuss the benefits and limitations of collaboration between veterinary medicine and the biomedical enterprise. [CREDIT: ROMAOSLO/iStockphoto]