Research ArticleCancer

Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer

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Science Translational Medicine  26 Aug 2015:
Vol. 7, Issue 302, pp. 302ra133
DOI: 10.1126/scitranslmed.aab0021

Article Information

vol. 7 no. 302 302ra133

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  • Received for publication March 2, 2015
  • Accepted for publication July 8, 2015
  • .

Author Information

  1. Isaac Garcia-Murillas1,*,
  2. Gaia Schiavon1,2,*,,
  3. Britta Weigelt3,
  4. Charlotte Ng3,
  5. Sarah Hrebien1,
  6. Rosalind J. Cutts1,
  7. Maggie Cheang4,
  8. Peter Osin2,
  9. Ashutosh Nerurkar2,
  10. Iwanka Kozarewa1,
  11. Javier Armisen Garrido1,
  12. Mitch Dowsett1,2,
  13. Jorge S. Reis-Filho3,
  14. Ian E. Smith2 and
  15. Nicholas C. Turner1,2,
  1. 1Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK.
  2. 2Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.
  3. 3Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  4. 4Institute of Cancer Research Clinical Trials and Statistics Unit, The Institute of Cancer Research, 15 Cotswold Road, Surrey SM2 5NG, UK.
  1. Corresponding author. E-mail: nicholas.turner{at}
    • * These authors contributed equally to this work.

    • Present address: Translational Science, Oncology iMed, AstraZeneca, Cambridge CB4 0WG, UK.


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