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Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis

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Science Translational Medicine  19 Aug 2015:
Vol. 7, Issue 301, pp. 301ra130
DOI: 10.1126/scitranslmed.3010467

Article Information

vol. 7 no. 301 301ra130

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History: 
  • Received for publication August 25, 2014
  • Accepted for publication July 15, 2015

Author Information

  1. Bo Ri Seo1,
  2. Priya Bhardwaj2,
  3. Siyoung Choi1,
  4. Jacqueline Gonzalez1,
  5. Roberto C. Andresen Eguiluz3,
  6. Karin Wang1,3,
  7. Sunish Mohanan4,
  8. Patrick G. Morris5,
  9. Baoheng Du2,
  10. Xi K. Zhou6,
  11. Linda T. Vahdat2,
  12. Akanksha Verma7,
  13. Olivier Elemento7,
  14. Clifford A. Hudis5,
  15. Rebecca M. Williams1,
  16. Delphine Gourdon3,
  17. Andrew J. Dannenberg2 and
  18. Claudia Fischbach1,8,*
  1. 1Department of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.
  2. 2Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
  3. 3Department of Materials Science and Engineering, Cornell University, Ithaca, NY 14853, USA.
  4. 4Department of Biological and Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
  5. 5Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  6. 6Department of Healthcare Policy and Research, Weill Cornell Medical College, New York, NY 10065, USA.
  7. 7Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA.
  8. 8Kavli Institute at Cornell for Nanoscale Science, Cornell University, Ithaca, NY 14853, USA.
  1. *Corresponding author. E-mail: cf99{at}cornell.edu

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