Research ArticleAsthma

TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma

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Science Translational Medicine  19 Aug 2015:
Vol. 7, Issue 301, pp. 301ra129
DOI: 10.1126/scitranslmed.aab3142

Article Information

vol. 7 no. 301 301ra129

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 10, 2015
  • Accepted for publication July 2, 2015
  • .

Author Information

  1. David F. Choy1,*,
  2. Kevin M. Hart2,*,
  3. Lee A. Borthwick3,
  4. Aarti Shikotra4,
  5. Deepti R. Nagarkar1,
  6. Salman Siddiqui4,
  7. Guiquan Jia1,
  8. Chandra M. Ohri4,
  9. Emma Doran1,5,
  10. Kevin M. Vannella2,
  11. Claire A. Butler5,
  12. Beverley Hargadon4,
  13. Joshua C. Sciurba2,
  14. Richard L. Gieseck2,
  15. Robert W. Thompson2,
  16. Sandra White2,
  17. Alexander R. Abbas1,
  18. Janet Jackman1,
  19. Lawren C. Wu1,
  20. Jackson G. Egen1,
  21. Liam G. Heaney5,
  22. Thirumalai R. Ramalingam2,
  23. Joseph R. Arron1,,,
  24. Thomas A. Wynn2, and
  25. Peter Bradding4,
  1. 1Genentech Inc., South San Francisco, CA 94080, USA.
  2. 2Program in Tissue Immunity and Repair, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  3. 3Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  4. 4Institute for Lung Health, Department of Infection, Immunity and Inflammation, University of Leicester, Leicester LE3 9QP, UK.
  5. 5Centre for Infection and Immunity, Health Sciences Building, Queens University Belfast, Lisburn Road, Belfast BT9 7AB, Northern Ireland, UK.
  1. Corresponding author. E-mail: arron.joseph{at}gene.com
    • * These authors contributed equally to this work.

    • These authors are co-senior authors.

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