Research ArticleCancer

Tyrosine kinase inhibitor–induced CD70 expression mediates drug resistance in leukemia stem cells by activating Wnt signaling

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Science Translational Medicine  29 Jul 2015:
Vol. 7, Issue 298, pp. 298ra119
DOI: 10.1126/scitranslmed.aab1740

Article Information

vol. 7 no. 298 298ra119

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 21, 2015
  • Accepted for publication June 26, 2015
  • .

Author Information

  1. Carsten Riether1,*,
  2. Christian M. Schürch1,2,*,
  3. Christoph Flury1,
  4. Magdalena Hinterbrandner1,
  5. Linda Drück1,
  6. Anne-Laure Huguenin1,
  7. Gabriela M. Baerlocher3,4,
  8. Ramin Radpour1 and
  9. Adrian F. Ochsenbein1,5,
  1. 1Tumor Immunology, Department of Clinical Research, University of Bern, Murtenstrasse 35, 3010 Bern, Switzerland.
  2. 2Institute of Pathology, University of Bern, Murtenstrasse 31, 3010 Bern, Switzerland.
  3. 3Experimental Hematology, Department of Clinical Research, Inselspital, University Hospital and University of Bern, 3010 Bern, Switzerland.
  4. 4Department of Hematology, Inselspital, University Hospital and University of Bern, 3010 Bern, Switzerland.
  5. 5Department of Medical Oncology, Inselspital, University Hospital and University of Bern, 3010 Bern, Switzerland.
  1. Corresponding author. E-mail: adrian.ochsenbein{at}insel.ch
    • * These authors contributed equally to this work.

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