Research ArticleDRUG RESISTANCE

Fitness cost of antibiotic susceptibility during bacterial infection

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Science Translational Medicine  22 Jul 2015:
Vol. 7, Issue 297, pp. 297ra114
DOI: 10.1126/scitranslmed.aab1621

Article Information

vol. 7 no. 297 297ra114

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History: 
  • Received for publication March 19, 2015
  • Accepted for publication May 27, 2015
  • .

Author Information

  1. Damien Roux1,2,3,*,
  2. Olga Danilchanka4,*,
  3. Thomas Guillard1,5,,
  4. Vincent Cattoir4,6,,
  5. Hugues Aschard7,
  6. Yang Fu4,
  7. Francois Angoulvant8,
  8. Jonathan Messika2,
  9. Jean-Damien Ricard2,
  10. John J. Mekalanos4,
  11. Stephen Lory4,
  12. Gerald B. Pier1, and
  13. David Skurnik1,
  1. 1Division of Infectious Diseases, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  2. 2INSERM, IAME, UMR 1137, F-75018 Paris, France.
  3. 3Université Paris Diderot, Sorbonne Paris Cité, F-75018 Paris, France.
  4. 4Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  5. 5EA 4687, Faculté de Médecine, Université de Reims Champagne-Ardenne, 51092 Reims, France.
  6. 6EA 4655, Faculté de Médecine, Université de Caen Basse-Normandie, 14033 Caen, France.
  7. 7Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.
  8. 8Hôpitaux de Paris (AP-HP), Pédiatrique Emergency Département, Hôpital Necker-Enfants Malades and Université Paris Descartes, 75015 Paris, France.
  1. Corresponding author. E-mail: gpier{at}bwh.harvard.edu (G.B.P.); dskurnik{at}rics.bwh.harvard.edu (D.S.)
    • * These authors contributed equally to this work (co–first authors).

    • These authors contributed equally to this work (co–second authors).

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