FocusCancer

Delineating cancer evolution with single-cell sequencing

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Science Translational Medicine  15 Jul 2015:
Vol. 7, Issue 296, pp. 296fs29
DOI: 10.1126/scitranslmed.aac8319

Figures

  • Fig. 1 No tumor cells are identical.

    Whole-genome single-cell sequencing of four tumor cells from an estrogen receptor–positive breast cancer patient shows that no two tumor cells are genetically identical. Clonal mutations are shown in black, subclonal mutations in intergenic regions are colored in red, and subclonal mutations in exonic regions are shown in green.

    CREDIT: ADAPTED BY PERMISSION FROM MACMILLAN PUBLISHERS LTD.: Y. WANG ET AL. (7), © 2014

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