Research ArticleCancer
Epigenetic therapy overcomes treatment resistance in T cell prolymphocytic leukemia
- Zainul S. Hasanali1,
- Bikramajit Singh Saroya2,
- August Stuart3,
- Sara Shimko3,
- Juanita Evans4,
- Mithun Vinod Shah5,
- Kamal Sharma6,
- Violetta V. Leshchenko7,
- Samir Parekh7,
- Thomas P. Loughran Jr.8,* and
- Elliot M. Epner9,*
- 1Department of Microbiology and Immunology, Pennsylvania State University College of Medicine and Penn State Hershey Cancer Institute, Hershey, PA 17033, USA.
- 2Department of Pathology, St. George's University, True Blue, Grenada.
- 3Department of Medicine/Hematology-Oncology, Pennsylvania State University College of Medicine and Penn State Hershey Cancer Institute, Hershey, PA 17033, USA.
- 4Department of Anatomic Pathology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
- 5Division of Hematology and Department of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.
- 6Shaner Cancer Center Mount Nittany Medical Center/Pennsylvania State University, State College, PA 6803, USA.
- 7Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
- 8Department of Medicine/Hematology-Oncology, UVA Cancer Center, Charlottesville, VA 22903, USA.
- 9Department of Hematology/Oncology, New Mexico VA Health Care System, Albuquerque, NM 87108, USA.
- ↵*Corresponding author. E-mail: tploughran{at}virginia.edu (T.P.L.); epner5{at}msn.com (E.M.E.)
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Science Translational Medicine 24 Jun 2015:
Vol. 7, Issue 293, pp. 293ra102
DOI: 10.1126/scitranslmed.aaa5079
Vol. 7, Issue 293, pp. 293ra102
DOI: 10.1126/scitranslmed.aaa5079
Zainul S. Hasanali
1Department of Microbiology and Immunology, Pennsylvania State University College of Medicine and Penn State Hershey Cancer Institute, Hershey, PA 17033, USA.
Bikramajit Singh Saroya
2Department of Pathology, St. George's University, True Blue, Grenada.
August Stuart
3Department of Medicine/Hematology-Oncology, Pennsylvania State University College of Medicine and Penn State Hershey Cancer Institute, Hershey, PA 17033, USA.
Sara Shimko
3Department of Medicine/Hematology-Oncology, Pennsylvania State University College of Medicine and Penn State Hershey Cancer Institute, Hershey, PA 17033, USA.
Juanita Evans
4Department of Anatomic Pathology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
Mithun Vinod Shah
5Division of Hematology and Department of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Kamal Sharma
6Shaner Cancer Center Mount Nittany Medical Center/Pennsylvania State University, State College, PA 6803, USA.
Violetta V. Leshchenko
7Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Samir Parekh
7Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Thomas P. Loughran Jr.
8Department of Medicine/Hematology-Oncology, UVA Cancer Center, Charlottesville, VA 22903, USA.
Elliot M. Epner
9Department of Hematology/Oncology, New Mexico VA Health Care System, Albuquerque, NM 87108, USA.
