Research ArticleType 1 Diabetes

Insulin B chain 9–23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs

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Science Translational Medicine  27 May 2015:
Vol. 7, Issue 289, pp. 289ra81
DOI: 10.1126/scitranslmed.aaa3032

Article Information

vol. 7 no. 289 289ra81

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication November 14, 2014
  • Accepted for publication April 6, 2015
  • .

Author Information

  1. Mahzad Akbarpour 1 , 2 , *,
  2. Kevin S. Goudy 1 , *,
  3. Alessio Cantore 1 ,
  4. Fabio Russo 1 ,
  5. Francesca Sanvito 3 ,
  6. Luigi Naldini 1 , 2 ,
  7. Andrea Annoni 1 , and
  8. Maria Grazia Roncarolo 1 , 2 , 4 , ,
  1. 1San Raffaele Telethon Institute for Gene Therapy, Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy.
  2. 2Vita-Salute San Raffaele University, Milan 20132, Italy.
  3. 3Pathology Unit, Department of Oncology, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy.
  4. 4Department of Pediatrics, Stanford School of Medicine, Stanford, CA 94305, USA.
  1. Corresponding author. E-mail: mg1{at}stanford.edu
    • * These authors contributed equally to this work.

    • These authors share senior authorship.

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