Research ArticleBLOOD-BRAIN BARRIER

Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier

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Science Translational Medicine  22 Apr 2015:
Vol. 7, Issue 284, pp. 284ra59
DOI: 10.1126/scitranslmed.aaa4304

Article Information

vol. 7 no. 284 284ra59

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication December 5, 2014
  • Accepted for publication April 2, 2015
  • .

Author Information

  1. Helen M. Lazear 1 , *,
  2. Brian P. Daniels 2 , *,
  3. Amelia K. Pinto 1 ,
  4. Albert C. Huang 3 ,
  5. Sarah C. Vick 1 , ,
  6. Sean E. Doyle 4 ,
  7. Michael Gale Jr. 3 ,
  8. Robyn S. Klein 1 , 2 , 5 , * , and
  9. Michael S. Diamond 1 , 5 , 6 , * ,
  1. 1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  2. 2Department of Anatomy & Neurobiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  3. 3Department of Immunology, University of Washington School of Medicine, Seattle, WA 98195, USA.
  4. 4ZymoGenetics, a Bristol-Myers Squibb Company, Seattle, WA 98102, USA.
  5. 5Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  6. 6Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  1. Corresponding author. E-mail: diamond{at}borcim.wustl.edu (M.S.D.); rklein{at}dom.wustl.edu (R.S.K.)
    • * These authors contributed equally to this work.

    • Present address: Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599, USA.

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