Research ArticleHuman Immunology

Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo

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Science Translational Medicine  22 Apr 2015:
Vol. 7, Issue 284, pp. 284ra56
DOI: 10.1126/scitranslmed.aaa1983

Article Information

vol. 7 no. 284 284ra56

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication October 30, 2014
  • Accepted for publication February 13, 2015
  • .

Author Information

  1. Julia Cuende1,*,
  2. Stéphanie Liénart1,*,
  3. Olivier Dedobbeleer1,
  4. Bas van der Woning2,
  5. Gitte De Boeck2,
  6. Julie Stockis1,
  7. Caroline Huygens1,
  8. Didier Colau3,
  9. Joan Somja4,
  10. Philippe Delvenne4,
  11. Muriel Hannon4,
  12. Frédéric Baron4,
  13. Laure Dumoutier3,
  14. Jean-Christophe Renauld3,
  15. Hans De Haard2,
  16. Michael Saunders2,
  17. Pierre G. Coulie1 and
  18. Sophie Lucas1,
  1. 1de Duve Institute, Université catholique de Louvain, and WELBIO, B1200 Brussels, Belgium.
  2. 2arGEN-X BVBA, Technologiepark 30, B9052 Zwijnaarde, Gent, Belgium.
  3. 3Ludwig Cancer Research, B1200 Brussels, Belgium.
  4. 4Department of Pathology, University Hospital of Liège, and Interdisciplinary Cluster of Applied Genoproteomics (GIGA), Laboratory of Experimental Pathology, University of Liège, B4000 Liège, Belgium.
  1. Corresponding author. E-mail: sophie.lucas{at}uclouvain.be
    • * These authors contributed equally to this work.

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