Research ArticleDrug Discovery

Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection

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Science Translational Medicine  08 Apr 2015:
Vol. 7, Issue 282, pp. 282ra49
DOI: 10.1126/scitranslmed.3010286

Article Information

vol. 7 no. 282 282ra49

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Print ISSN: 
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History: 
  • Received for publication August 7, 2014
  • Accepted for publication February 20, 2015
  • .

Author Information

  1. Shanshan He1,
  2. Billy Lin1,
  3. Virginia Chu1,
  4. Zongyi Hu1,
  5. Xin Hu2,
  6. Jingbo Xiao2,
  7. Amy Q. Wang2,
  8. Cameron J. Schweitzer1,
  9. Qisheng Li1,
  10. Michio Imamura3,
  11. Nobuhiko Hiraga3,
  12. Noel Southall2,
  13. Marc Ferrer2,
  14. Wei Zheng2,
  15. Kazuaki Chayama3,
  16. Juan J. Marugan2 and
  17. T. Jake Liang1,*
  1. 1Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  2. 2National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA.
  3. 3Department of Medicine and Molecular Sciences, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 730-0053, Japan.
  1. *Corresponding author. E-mail: jliang{at}nih.gov

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