Research ArticleCancer

Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAFV600E melanoma

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Science Translational Medicine  18 Mar 2015:
Vol. 7, Issue 279, pp. 279ra41
DOI: 10.1126/scitranslmed.aaa4691

Article Information

vol. 7 no. 279 279ra41

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication October 24, 2014
  • Accepted for publication January 27, 2015

Author Information

  1. Siwen Hu-Lieskovan1,
  2. Stephen Mok1,
  3. Blanca Homet Moreno1,2,
  4. Jennifer Tsoi3,4,
  5. Lidia Robert1,
  6. Lucas Goedert1,
  7. Elaine M. Pinheiro5,
  8. Richard C. Koya1,*,
  9. Thomas G. Graeber3,4,6,
  10. Begoña Comin-Anduix6,7 and
  11. Antoni Ribas1,4,6,7,
  1. 1Division of Hematology-Oncology, Department of Medicine, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
  2. 2Division of Translational Oncology, Carlos III Health Institute, Madrid 28029, Spain.
  3. 3Crump Institute for Molecular Imaging, UCLA, Los Angeles, CA 90095, USA.
  4. 4Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, CA 90095, USA.
  5. 5Merck Research Laboratories, Boston, MA 02115, USA.
  6. 6Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA 90095, USA.
  7. 7Division of Surgical Oncology, Department of Surgery, UCLA, Los Angeles, CA 90095, USA.
  1. Corresponding author. E-mail: aribas{at}mednet.ucla.edu
  • * Present address: Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

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